XRCC2

Description		X-ray repair cross complementing 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Four-way Junction DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA
	Biological Process	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination In Utero Embryonic Development Somitogenesis DNA Repair Centrosome Cycle Response To X-ray Response To Gamma Radiation Multicellular Organism Growth Strand Invasion Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neurogenesis Meiotic Cell Cycle Regulation Of Fibroblast Apoptotic Process
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Drugs
Diseases
GWAS		Diabetic kidney disease ( 26305897) Mean platelet volume ( 32888494 27863252) Palmitic acid (16:0) levels ( 23362303)
Interacting Genes		5 interacting genes: MEOX2 NKIRAS1 RAD51 RAD51D WFDC1
Entrez ID		7516
HPRD ID		02656
Ensembl ID		ENSG00000196584
Uniprot IDs		A0A384MEK2 O43543
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?