HiPPIP
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HIRA

Description histone cell cycle regulator
Image
GO Annotations Cellular Component
  • HIR Complex
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • PML Body
  • Protein-containing Complex
  • Extracellular Exosome
Molecular Function
  • Transcription Corepressor Activity
  • Protein Binding
  • Nucleosome Binding
  • Histone Binding
  • RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Biological Process
  • DNA Replication-independent Nucleosome Assembly
  • Transcription, DNA-templated
  • Regulation Of Transcription By RNA Polymerase II
  • Anatomical Structure Morphogenesis
  • Negative Regulation Of Transcription, DNA-templated
Pathways
  • Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes 16 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 TRIM55 TRIM63 UBE2I UPF1
Entrez ID 7290
HPRD ID 02583
Ensembl ID ENSG00000100084
Uniprot IDs P54198
PDB IDs 2I32 5YJE
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025