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TPTE

Description transmembrane phosphatase with tensin homology
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • Plasma Membrane
  • Integral Component Of Membrane
  • Cell Projection
Molecular Function
  • Protein Tyrosine Phosphatase Activity
  • Protein Tyrosine/serine/threonine Phosphatase Activity
  • Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
Biological Process
  • Protein Dephosphorylation
  • Signal Transduction
  • Negative Regulation Of Cell Population Proliferation
  • Phosphatidylinositol 3-kinase Signaling
  • Dephosphorylation
  • Peptidyl-tyrosine Dephosphorylation
  • Phosphatidylinositol Dephosphorylation
  • Cell Motility
  • Regulation Of Protein Kinase B Signaling
Pathways
  • Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS
  • Celiac disease ( 23936387)
Interacting Genes 11 interacting genes: ADRB2 EPHA1 EPHA2 EPHA3 ERBB3 MEOX2 NTRK1 PDGFRB PTK7 ROR2 TUBB3
Entrez ID 7179
HPRD ID 05064
Ensembl ID ENSG00000274391
Uniprot IDs P56180
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025