ST14

Description		ST14 transmembrane serine protease matriptase
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching
Pathways		Formation of the cornified envelope Formation of the cornified envelope
Drugs		Urokinase Benzamidine Camostat
Diseases
GWAS		Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		18 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NFRKB NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1
Entrez ID		6768
HPRD ID		06005
Ensembl ID		ENSG00000149418
Uniprot IDs		Q9Y5Y6
PDB IDs		1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T 6T9T
Enriched GO Terms of Interacting Partners?
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