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FOXL2

Description forkhead box L2
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • Flemming Body
Molecular Function
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA Binding
  • DNA-binding Transcription Factor Activity
  • Protein Binding
  • Ubiquitin Conjugating Enzyme Binding
  • Cysteine-type Endopeptidase Regulator Activity Involved In Apoptotic Process
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Ovarian Follicle Development
  • Extraocular Skeletal Muscle Development
  • Apoptotic DNA Fragmentation
  • Regulation Of Transcription By RNA Polymerase II
  • Anatomical Structure Morphogenesis
  • Cell Differentiation
  • Positive Regulation Of Apoptotic Process
  • Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription, DNA-templated
Pathways
  • SUMOylation of transcription factors
Drugs
Diseases
GWAS
  • Ear morphology ( 26105758)
  • Eyebrow thickness ( 30248107 26926045)
  • Keloid ( 20711176)
  • Lobe attachment (rater scored) ( 29198719)
  • Lobe attachment (rater-scored or self-reported) ( 29198719)
  • Lobe size ( 26105758)
  • Male-pattern baldness ( 28196072)
Interacting Genes 3 interacting genes: LATS1 PAK1 UBE2I
Entrez ID 668
HPRD ID 05723
Ensembl ID ENSG00000183770
Uniprot IDs P58012 Q53ZD3
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025