BOK

Description		BCL2 family apoptosis regulator BOK
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GO Annotations	Cellular Component	Nucleus Nuclear Outer Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Integral Component Of Membrane Early Endosome Membrane Mitochondrial Membrane Trans-Golgi Network Membrane Cis-Golgi Network Membrane Recycling Endosome Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding
	Biological Process	Release Of Cytochrome C From Mitochondria Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Brain Development Male Gonad Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Regulation Of Autophagy Positive Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Oligodendrocyte Differentiation Protein Complex Oligomerization Neuron Apoptotic Process Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Mitochondrial Depolarization Negative Regulation Of Necroptotic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Chorionic Trophoblast Cell Proliferation Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Granulosa Cell Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Brain structure ( 20171287) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Planum temporale asymmetry index ( 31887566) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		3 interacting genes: BCL2A1 MCL1 NOA1
Entrez ID		666
HPRD ID		05657
Ensembl ID		ENSG00000176720
Uniprot IDs		A0A024R4A8 A0A481T0W6 A0A4D6NU76 Q9UMX3
PDB IDs		6CKV
Enriched GO Terms of Interacting Partners?
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