DDRGK1

Description		DDRGK domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Ubiquitin-like Protein Ligase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Cartilage Development Reticulophagy Protein Localization To Endoplasmic Reticulum Protein Ufmylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of I-kappaB Phosphorylation Negative Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Metallopeptidase Activity Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Protein K69-linked Ufmylation
Pathways		RHOA GTPase cycle
Drugs
Diseases
GWAS		HDL cholesterol levels x loop diuretics use interaction ( 31806883) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Night sleep phenotypes ( 27126917) Parkinson's disease ( 25064009 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Response to hepatitis C treatment ( 21659334) Ribavirin-induced anemia ( 20637204)
Interacting Genes		5 interacting genes: APP FASTKD5 FBXO7 HTR6 TP53
Entrez ID		65992
HPRD ID		12741
Ensembl ID		ENSG00000198171
Uniprot IDs		Q96HY6
PDB IDs
Enriched GO Terms of Interacting Partners?
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