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UPF3B

Description UPF3B regulator of nonsense mediated mRNA decay
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Cytoplasm
  • Cytosol
  • Centriolar Satellite
  • Exon-exon Junction Complex
Molecular Function
  • RNA Binding
  • MRNA Binding
  • Protein Binding
  • Structural Constituent Of Nuclear Pore
Biological Process
  • Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
  • Nucleocytoplasmic Transport
  • Positive Regulation Of Translation
  • MRNA Transport
Pathways
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes 14 interacting genes: EIF4A3 EIF6 EXOSC4 HBB MAGOH MCRS1 OGT RBBP6 RBM8A SRPK2 TTC19 UPF1 UPF2 XRN1
Entrez ID 65109
HPRD ID 02247
Ensembl ID ENSG00000125351
Uniprot IDs Q9BZI7
PDB IDs 1UW4 2XB2
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025