DCLRE1B

Description		DNA cross-link repair 1B
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Cytoplasm Centrosome Nuclear Body
	Molecular Function	Damaged DNA Binding Protein Binding 5'-3' Exonuclease Activity 5'-3' Exodeoxyribonuclease Activity Protein Homodimerization Activity Protein-containing Complex Binding
	Biological Process	Telomere Maintenance Double-strand Break Repair Via Nonhomologous End Joining Telomere Maintenance Via Telomere Lengthening Telomere Capping Telomeric Loop Formation Protection From Non-homologous End Joining At Telomere Telomeric 3' Overhang Formation Interstrand Cross-link Repair Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Fanconi Anemia Pathway
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Breast cancer ( 29059683 23535729) Coronary artery disease ( 33020668) Crohn's disease ( 28067908 23128233) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965)
Interacting Genes		2 interacting genes: NOXA1 TRIM54
Entrez ID		64858
HPRD ID		16785
Ensembl ID		ENSG00000118655
Uniprot IDs		Q9H816
PDB IDs		3BUA 5AHO 7A1F 7B2X 7B9B
Enriched GO Terms of Interacting Partners?
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