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RNF6

Description ring finger protein 6
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • PML Body
  • Axon
  • Nuclear Membrane
  • Intracellular Membrane-bounded Organelle
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Metal Ion Binding
  • Androgen Receptor Binding
  • Ubiquitin Protein Ligase Activity
Biological Process
  • Regulation Of Transcription, DNA-templated
  • Ubiquitin-dependent Protein Catabolic Process
  • Protein Ubiquitination
  • Negative Regulation Of Axon Extension
  • Protein K27-linked Ubiquitination
  • Positive Regulation Of Transcription, DNA-templated
  • Regulation Of Androgen Receptor Signaling Pathway
  • Protein K48-linked Ubiquitination
  • Protein K6-linked Ubiquitination
Pathways
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Sporadic pituitary adenoma ( 26029870)
  • Type 2 diabetes ( 24509480 30297969 32499647 30718926 28869590)
  • Urate levels (BMI interaction) ( 25811787)
Interacting Genes 36 interacting genes: AHCYL1 AR CBY2 CCDC33 CCDC57 CEP70 GOLGA2 HOOK2 IKZF1 IKZF3 KIAA0753 KRT15 KRT40 LDOC1 MAGED1 MDFI MEOX2 MID2 MIPOL1 MTUS2 PNMA2 REL RINT1 RPGRIP1 SSX2IP STX11 TADA2A TCF4 TFIP11 TNS2 TRIM23 TRIM27 TRIM37 TSGA10 UBE2D1 UBE2H
Entrez ID 6049
HPRD ID 05027
Ensembl ID ENSG00000127870
Uniprot IDs A0A024RDP2 A0A0S2Z4G9 Q9Y252
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025