RFC4

Description		replication factor C subunit 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor C Complex Ctf18 RFC-like Complex Elg1 RFC-like Complex
	Molecular Function	DNA Binding DNA Clamp Loader Activity Protein Binding ATP Binding Single-stranded DNA Helicase Activity
	Biological Process	DNA-dependent DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Repair DNA Duplex Unwinding Positive Regulation Of DNA-directed DNA Polymerase Activity
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere Activation of ATR in response to replication stress PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Single Strand Annealing (SSA) HDR through Homologous Recombination (HRR) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Regulation of TP53 Activity through Phosphorylation Polymerase switching G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881)
Interacting Genes		13 interacting genes: BRD4 CDK4 CHTF18 HDAC1 PCNA PTEN RAD17 RFC2 RFC3 RFC5 RNF41 SUMO2 TRIM28
Entrez ID		5984
HPRD ID		00022
Ensembl ID		ENSG00000163918
Uniprot IDs		P35249
PDB IDs		6VVO
Enriched GO Terms of Interacting Partners?
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