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RFC2
Description
replication factor C subunit 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
DNA Replication Factor C Complex
Ctf18 RFC-like Complex
Molecular Function
DNA Binding
DNA Clamp Loader Activity
Protein Binding
ATP Binding
Single-stranded DNA Helicase Activity
Enzyme Binding
Biological Process
DNA-dependent DNA Replication
DNA Repair
DNA Duplex Unwinding
Positive Regulation Of DNA-directed DNA Polymerase Activity
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Activation of ATR in response to replication stress
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Activity through Phosphorylation
Polymerase switching
G2/M DNA damage checkpoint
Drugs
Diseases
GWAS
Interacting Genes
13 interacting genes:
EIF4H
HGS
PCNA
PRKAR1A
PSMA1
RAD17
RAD18
RFC1
RFC4
RFC5
SUMO2
YOD1
ZIC1
Entrez ID
5982
HPRD ID
02675
Ensembl ID
ENSG00000049541
Uniprot IDs
A0A087WVY3
P35250
Q75MT5
PDB IDs
6VVO
Enriched GO Terms of Interacting Partners
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