SNX6

Description		sorting nexin 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cytosol Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Tubular Endosome
	Molecular Function	Protein Binding Dynactin Binding Type I Transforming Growth Factor Beta Receptor Binding Phosphatidylinositol Binding Protein Homodimerization Activity
	Biological Process	Intracellular Protein Transport Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Macroautophagy Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Retrograde Transport, Endosome To Golgi Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Histamine Secretion By Mast Cell Cellular Response To Amyloid-beta
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Celiac disease ( 23936387) Diastolic blood pressure ( 30224653) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		27 interacting genes: ACVR2B ACVRL1 BMPR1B BRCA1 BRMS1 CALM1 COIL CSNK2A2 DISC1 EGFR ESR1 INSR LEPR NDEL1 OGT OPTN PDGFRA PIM1 RAG1 SNX1 SNX2 SNX4 TEX11 TGFBR1 TGFBR2 TNIK TPT1
Entrez ID		58533
HPRD ID		12086
Ensembl ID		ENSG00000129515
Uniprot IDs		A0A0A0MRI2 Q9UNH7
PDB IDs
Enriched GO Terms of Interacting Partners?
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