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NKX3-2

Description NK3 homeobox 2
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
Molecular Function
  • RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
  • Protein Binding
  • Sequence-specific Double-stranded DNA Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Skeletal System Development
  • Regulation Of Transcription By RNA Polymerase II
  • Transcription By RNA Polymerase II
  • Determination Of Left/right Symmetry
  • Cell Differentiation
  • Pancreas Development
  • Negative Regulation Of Chondrocyte Differentiation
  • Middle Ear Morphogenesis
  • Negative Regulation Of Apoptotic Process
  • Spleen Development
  • Animal Organ Formation
  • Skeletal System Morphogenesis
  • Embryonic Skeletal System Development
  • Intestinal Epithelial Cell Development
Pathways
  • Regulation of RUNX2 expression and activity
Drugs
Diseases
GWAS
  • Metabolite levels ( 23823483)
  • Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes 5 interacting genes: GRPEL1 HDAC1 POU6F2 SMAD1 SMAD4
Entrez ID 579
HPRD ID 09075
Ensembl ID ENSG00000109705
Uniprot IDs P78367
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025