CHD8

Description		chromodomain helicase DNA binding protein 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Protein-containing Complex MLL1 Complex
	Molecular Function	P53 Binding DNA Binding DNA Helicase Activity Chromatin Binding Protein Binding ATP Binding Beta-catenin Binding ATP-dependent Activity, Acting On DNA ATP Hydrolysis Activity Methylated Histone Binding Histone Binding Armadillo Repeat Domain Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Chromatin Remodeling Brain Development Wnt Signaling Pathway DNA Duplex Unwinding Social Behavior Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Digestive Tract Development Prepulse Inhibition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Fibroblast Apoptotic Process
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Height ( 31562340) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		11 interacting genes: AR ASH2L CHD7 CREB1 CTCF CTNNB1 RBBP5 RCHY1 SUMO2 TOP3B WDR5
Entrez ID		57680
HPRD ID		16712
Ensembl ID		ENSG00000100888
Uniprot IDs		Q9HCK8
PDB IDs		2CKA 2DL6
Enriched GO Terms of Interacting Partners?
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