HECW2

Description		HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
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GO Annotations	Cellular Component	Cytoplasm Mitotic Spindle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination Regulation Of Mitotic Metaphase/anaphase Transition Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Dendrite Morphogenesis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes		8 interacting genes: CBX1 CBX3 CBX5 FZR1 TP73 UBE2D2 UBE2D3 UBE2L3
Entrez ID		57520
HPRD ID		17099
Ensembl ID		ENSG00000138411
Uniprot IDs		A0A2R8Y6F3 Q9P2P5
PDB IDs		2LFE
Enriched GO Terms of Interacting Partners?
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