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TIGAR
Description
TP53 induced glycolysis regulatory phosphatase
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrial Outer Membrane
Cytosol
Molecular Function
Bisphosphoglycerate 2-phosphatase Activity
Fructose-2,6-bisphosphate 2-phosphatase Activity
Protein Binding
Biological Process
Response To Ischemia
Fructose 2,6-bisphosphate Metabolic Process
Autophagy
Apoptotic Process
Cellular Response To DNA Damage Stimulus
Response To Xenobiotic Stimulus
Response To Gamma Radiation
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Dephosphorylation
Fructose 1,6-bisphosphate Metabolic Process
Negative Regulation Of Programmed Cell Death
Regulation Of Pentose-phosphate Shunt
Positive Regulation Of DNA Repair
Negative Regulation Of Glycolytic Process
Intestinal Epithelial Cell Development
Cellular Response To Cobalt Ion
Cellular Response To Hypoxia
Negative Regulation Of Neuron Death
Negative Regulation Of Mitophagy
Regulation Of Response To DNA Damage Checkpoint Signaling
Positive Regulation Of Hexokinase Activity
Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
TP53 Regulates Metabolic Genes
Drugs
Diseases
GWAS
Interacting Genes
2 interacting genes:
APP
RPL11
Entrez ID
57103
HPRD ID
12610
Ensembl ID
ENSG00000078237
Uniprot IDs
Q9NQ88
PDB IDs
3DCY
Enriched GO Terms of Interacting Partners
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