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PROS1

Description protein S
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Extracellular Region
  • Extracellular Space
  • Endoplasmic Reticulum Membrane
  • Golgi Lumen
  • Plasma Membrane
  • Platelet Alpha Granule Lumen
  • Extracellular Exosome
  • Blood Microparticle
Molecular Function
  • Endopeptidase Inhibitor Activity
  • Calcium Ion Binding
  • Protein Binding
Biological Process
  • Blood Coagulation
  • Negative Regulation Of Endopeptidase Activity
  • Fibrinolysis
Pathways
  • Platelet degranulation
  • Intrinsic Pathway of Fibrin Clot Formation
  • Common Pathway of Fibrin Clot Formation
  • Gamma-carboxylation of protein precursors
  • Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
  • Removal of aminoterminal propeptides from gamma-carboxylated proteins
  • Cell surface interactions at the vascular wall
  • Regulation of Complement cascade
Drugs
  • Drotrecogin alfa
  • Menadione
  • Sodium tetradecyl sulfate
  • Kappadione
Diseases
GWAS
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 12 interacting genes: ARL6 C4BPA C4BPB F10 F2 F5 F8 HSP90AB1 PROC RPSA TBK1 TYRO3
Entrez ID 5627
HPRD ID 01473
Ensembl ID ENSG00000184500
Uniprot IDs A0A0S2Z4K3 A0A0S2Z4L3 P07225
PDB IDs 1Z6C
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025