RCC2

Description		regulator of chromosome condensation 2
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GO Annotations	Cellular Component	Nucleolus Cytosol Microtubule Plasma Membrane Membrane Midbody Early Endosome Membrane Chromosome, Centromeric Core Domain Mitotic Spindle Midzone
	Molecular Function	RNA Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Microtubule Binding Protein Kinase Binding Protein Domain Specific Binding Small GTPase Binding
	Biological Process	Cell Cycle Integrin-mediated Signaling Pathway Regulation Of Fibroblast Migration Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Migration Negative Regulation Of GTPase Activity Establishment Of Protein Localization Focal Adhesion Assembly Cell Division Negative Regulation Of Focal Adhesion Assembly Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Chromosome Passenger Complex Localization To Kinetochore Activation Of GTPase Activity Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Ruffle Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Basal cell carcinoma ( 33549134 24403052 25855136 27539887 18849993) Non-melanoma skin cancer ( 29739929)
Interacting Genes		4 interacting genes: ERG PRPF40A PTEN RAC1
Entrez ID		55920
HPRD ID		18171
Ensembl ID		ENSG00000179051
Uniprot IDs		A0A024RAC5 Q9P258
PDB IDs		5GWN
Enriched GO Terms of Interacting Partners?
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