EDEM2

Description		ER degradation enhancing alpha-mannosidase like protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding
	Biological Process	Carbohydrate Metabolic Process Response To Unfolded Protein Viral Protein Processing Trimming Of Terminal Mannose On B Branch Trimming Of Terminal Mannose On C Branch Trimming Of First Mannose On A Branch Trimming Of Second Mannose On A Branch Ubiquitin-dependent Glycoprotein ERAD Pathway Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Mannose Trimming Involved In Glycoprotein ERAD Pathway
Pathways		ER Quality Control Compartment (ERQC) Maturation of spike protein
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Birth weight ( 31043758) Blood protein levels ( 28240269) Body shape index ( 34021172) Estimated glomerular filtration rate ( 31152163) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 30275531) Hemostatic factors and hematological phenotypes ( 22443383) Hip circumference adjusted for BMI ( 34021172) Liver enzyme levels (alkaline phosphatase) ( 33972514) Offspring birth weight ( 31043758) Protein C levels ( 28082259 20802025) Prothrombin time ( 22703881) QRS complex (Cornell) ( 27659466) Serum alkaline phosphatase levels ( 33547301) Venous thromboembolism ( 31676865) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: RPS3A TRPC4AP
Entrez ID		55741
HPRD ID		09841
Ensembl ID		ENSG00000088298
Uniprot IDs		Q9BV94
PDB IDs
Enriched GO Terms of Interacting Partners?
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