RNF43

Description		ring finger protein 43
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GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Frizzled Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Wnt Signaling Pathway Protein Ubiquitination Negative Regulation Of Wnt Signaling Pathway Wnt Receptor Catabolic Process Stem Cell Proliferation
Pathways		Regulation of FZD by ubiquitination Signaling by RNF43 mutants
Drugs
Diseases
GWAS		Circulating myeloperoxidase levels (plasma) ( 23620142) Cognitive function ( 25644384) Hemoglobin levels ( 32327693) Iron status biomarkers (ferritin levels) ( 33536631) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Pancreatic cancer ( 20686608) Prostate cancer ( 29892016) Refractive error ( 32231278) Stroke ( 29531354) Vitamin D levels ( 25208829)
Interacting Genes		9 interacting genes: MKS1 RSPO2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N
Entrez ID		54894
HPRD ID		07896
Ensembl ID		ENSG00000108375
Uniprot IDs		J3KSE3 Q68DV7
PDB IDs		4KNG
Enriched GO Terms of Interacting Partners?
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