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TPCN1

Description two pore segment channel 1
Image No pdb structure
GO Annotations Cellular Component
  • Lysosome
  • Lysosomal Membrane
  • Endosome
  • Endosome Membrane
  • Integral Component Of Membrane
  • Early Endosome Membrane
  • Endolysosome
  • Recycling Endosome Membrane
Molecular Function
  • Voltage-gated Calcium Channel Activity
  • Voltage-gated Sodium Channel Activity
  • Protein Binding
  • Ligand-gated Sodium Channel Activity
  • Syntaxin Binding
  • Identical Protein Binding
  • Protein Homodimerization Activity
  • NAADP-sensitive Calcium-release Channel Activity
  • Phosphatidylinositol-3,5-bisphosphate Binding
  • Intracellular Phosphatidylinositol-3,5-bisphosphate-sensitive Cation Channel Activity
Biological Process
  • Positive Regulation Of Autophagy
  • Ion Transmembrane Transport
  • Regulation Of Ion Transmembrane Transport
  • Sodium Ion Transmembrane Transport
  • Release Of Sequestered Calcium Ion Into Cytosol
  • Endocytosis Involved In Viral Entry Into Host Cell
Pathways
  • Stimuli-sensing channels
Drugs
Diseases
GWAS
  • Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes 1 interacting genes: IFT81
Entrez ID 53373
HPRD ID 18217
Ensembl ID ENSG00000186815
Uniprot IDs B3KSG7 B7Z3R2 Q9ULQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025