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PFKL

Description phosphofructokinase, liver type
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Cytosol
  • 6-phosphofructokinase Complex
  • Membrane
  • Secretory Granule Lumen
  • Extracellular Exosome
  • Ficolin-1-rich Granule Lumen
Molecular Function
  • 6-phosphofructokinase Activity
  • Protein Binding
  • ATP Binding
  • AMP Binding
  • Kinase Binding
  • Identical Protein Binding
  • Metal Ion Binding
  • Monosaccharide Binding
  • Fructose Binding
  • Fructose-6-phosphate Binding
Biological Process
  • Fructose 6-phosphate Metabolic Process
  • Glycolytic Process
  • Response To Glucose
  • Fructose 1,6-bisphosphate Metabolic Process
  • Negative Regulation Of Insulin Secretion
  • Canonical Glycolysis
Pathways
  • Neutrophil degranulation
  • Glycolysis
Drugs
Diseases
GWAS
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Hemoglobin levels ( 32327693)
  • Rheumatoid arthritis ( 21505073)
Interacting Genes 16 interacting genes: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PCNT PFKM PRPF40A SHANK3 SUMO2 TESK1 TNFAIP3 YWHAQ
Entrez ID 5211
HPRD ID 01385
Ensembl ID ENSG00000141959
Uniprot IDs P17858 Q7L2M7
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025