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PDK4

Description pyruvate dehydrogenase kinase 4
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Protein Kinase Activity
  • Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity
  • Protein Binding
  • ATP Binding
Biological Process
  • Glucose Metabolic Process
  • Protein Phosphorylation
  • Regulation Of PH
  • Insulin Receptor Signaling Pathway
  • Cellular Response To Starvation
  • Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate
  • Regulation Of Cellular Ketone Metabolic Process
  • Regulation Of Glucose Metabolic Process
  • Regulation Of Fatty Acid Biosynthetic Process
  • Glucose Homeostasis
  • Response To Starvation
  • Regulation Of Bone Resorption
  • Regulation Of Fatty Acid Oxidation
  • Cellular Response To Fatty Acid
  • Reactive Oxygen Species Metabolic Process
  • Negative Regulation Of Anoikis
Pathways
  • Regulation of pyruvate dehydrogenase (PDH) complex
  • Signaling by Retinoic Acid
Drugs
  • Tretinoin
  • 4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol
Diseases
GWAS
  • Refractive error ( 32231278)
Interacting Genes 5 interacting genes: DLAT PDHA1 PLEKHF2 REEP5 TRIM63
Entrez ID 5166
HPRD ID 03957
Ensembl ID ENSG00000004799
Uniprot IDs A4D1H4 Q16654
PDB IDs 2E0A 2ZDX 2ZDY 2ZKJ 3D2R
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025