CHMP3

Description		charged multivesicular body protein 3
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GO Annotations	Cellular Component	ESCRT III Complex Early Endosome Late Endosome Multivesicular Body Cytosol Plasma Membrane Midbody Cytoplasmic Vesicle Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylcholine Binding Ubiquitin-specific Protease Binding
	Biological Process	Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Macroautophagy Positive Regulation Of Cytokinesis Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Regulation Of Endosome Size Protein Polymerization Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Negative Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion Regulation Of Early Endosome To Late Endosome Transport
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Adult body size ( 32376654) Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence symptom count ( 25555482)
Interacting Genes		13 interacting genes: APP CHMP2A CHMP2B CHMP4A CHMP4B FBXO7 IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2
Entrez ID		51652
HPRD ID		15650
Ensembl ID		ENSG00000115561
Uniprot IDs		Q9Y3E7
PDB IDs		2GD5 2XZE 3FRT 3FRV
Enriched GO Terms of Interacting Partners?
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