TRIAP1

Description		TP53 regulated inhibitor of apoptosis 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Intermembrane Space Protein-containing Complex
	Molecular Function	P53 Binding Protein Binding Phosphatidic Acid Transfer Activity
	Biological Process	Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Phospholipid Transport DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To UV Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Membrane Lipid Distribution Intermembrane Lipid Transfer Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Phospholipid Transport
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Insulin resistance/response ( 21901158) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		7 interacting genes: AMY2A APAF1 HSPA1A LCN2 PLEKHF2 SBNO1 TP53
Entrez ID		51499
HPRD ID		13698
Ensembl ID		ENSG00000170855
Uniprot IDs		O43715
PDB IDs		4XZS 4XZV 6I3V 6I3Y 6I4Y
Enriched GO Terms of Interacting Partners?
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