TAOK3

Description		TAO kinase 3
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Transferase Activity Protein Serine Kinase Activity
	Biological Process	MAPK Cascade DNA Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Signaling Positive Regulation Of Stress-activated MAPK Cascade Intracellular Signal Transduction Negative Regulation Of Catalytic Activity Regulation Of MAPK Cascade Positive Regulation Of JUN Kinase Activity Negative Regulation Of JNK Cascade Positive Regulation Of JNK Cascade Protein Autophosphorylation Neuron Projection Morphogenesis
Pathways		RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle
Drugs		Fostamatinib
Diseases
GWAS		Depression ( 33859377) Glucose homeostasis traits ( 25524916) Hip circumference ( 28552196) Loneliness ( 31518406) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733) Post bronchodilator FEV1 in COPD ( 26634245) Red cell distribution width ( 32888494 27863252) Systemic lupus erythematosus ( 19838195)
Interacting Genes		5 interacting genes: ATF7 ERN1 LRRK2 SMURF1 TRAF2
Entrez ID		51347
HPRD ID		11620
Ensembl ID		ENSG00000135090
Uniprot IDs		G3V1Q8 Q9H2K8
PDB IDs		6BDN
Enriched GO Terms of Interacting Partners?
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