GP6

Description		glycoprotein VI platelet
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Raft Extracellular Exosome Tetraspanin-enriched Microdomain
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Collagen Binding Signaling Receptor Activity Protein Tyrosine Kinase Binding
	Biological Process	Enzyme Linked Receptor Protein Signaling Pathway Platelet Activation Collagen-activated Signaling Pathway Positive Regulation Of Platelet Aggregation
Pathways		GPVI-mediated activation cascade Cell surface interactions at the vascular wall Platelet Adhesion to exposed collagen
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Breast cancer and/or colorectal cancer ( 29698419) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Inflammatory biomarkers (multivariate analysis) ( 33110245) Mean platelet volume ( 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Platelet aggregation ( 20526338 29185836) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Venous thromboembolism ( 31420334)
Interacting Genes		7 interacting genes: CRP FCER1G FCGR2A FCGR3A FYN LYN YES1
Entrez ID		51206
HPRD ID		10406
Ensembl ID		ENSG00000088053
Uniprot IDs		Q9HCN6
PDB IDs		2GI7 5OU7 5OU8 5OU9
Enriched GO Terms of Interacting Partners?
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