OVOL1

Description		ovo like transcriptional repressor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Regulation Of Transcription By RNA Polymerase II Spermatogenesis Mesoderm Development Epidermal Cell Differentiation Skin Development Germline Cell Cycle Switching, Mitotic To Meiotic Cell Cycle Negative Regulation Of Meiotic Cell Cycle Phase Transition Negative Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181 30542056) Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic sensitization ( 30013184) Apolipoprotein A1 levels ( 32203549) Asthma ( 31361310 30929738 34103634 32296059 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Atopic dermatitis ( 23042114 22197932 26482879) Atopic march ( 26542096) Basal cell carcinoma ( 33549134) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 29875488) Body shape index ( 34021172) Breast cancer ( 23535729) Chronic kidney disease ( 20383146) DNA methylation (variation) ( 23725790) Eczema ( 31361310) Estimated glomerular filtration rate ( 31451708) High density lipoprotein cholesterol levels ( 31928498) Hip circumference adjusted for BMI ( 34021172) IgG N-glycosylation phenotypes (multivariate analysis) ( 33710309) Medication use (diuretics) ( 31015401) Rosacea symptom severity ( 29771307) Serum uric acid levels ( 30993211) Systemic lupus erythematosus ( 33272962 26502338 28714469) Systolic blood pressure ( 31928498) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Urate levels ( 23263486) Waist circumference ( 31928498) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: FAM90A1 LMNB2 MAFF
Entrez ID		5017
HPRD ID		09080
Ensembl ID		ENSG00000172818
Uniprot IDs		G3V1B0 O14753
PDB IDs
Enriched GO Terms of Interacting Partners?
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