NTF3

Description		neurotrophin 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Synaptic Vesicle Axon Dendrite
	Molecular Function	Signaling Receptor Binding Nerve Growth Factor Receptor Binding Protein Binding Growth Factor Activity Chemoattractant Activity
	Biological Process	Positive Regulation Of Receptor Internalization Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling Nervous System Development Peripheral Nervous System Development Memory Positive Regulation Of Cell Population Proliferation Nerve Development Positive Regulation Of Cell Migration Activation Of Protein Kinase B Activity Positive Regulation Of Peptidyl-serine Phosphorylation Nerve Growth Factor Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Neuron Apoptotic Process Regulation Of Neuron Differentiation Neuron Projection Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Modulation Of Chemical Synaptic Transmission Positive Chemotaxis Induction Of Positive Chemotaxis Activation Of GTPase Activity Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways		NTF3 activates NTRK2 (TRKB) signaling NTF3 activates NTRK3 signaling NTF3 activates NTRK3 signaling Signaling by NTRK3 (TRKC) Activated NTRK3 signals through PLCG1 Activated NTRK3 signals through PLCG1 Activated NTRK3 signals through RAS Activated NTRK3 signals through PI3K Activated NTRK3 signals through PI3K
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Insomnia ( 29520036)
Interacting Genes		7 interacting genes: BDNF LRP1 MEOX2 NTRK1 NTRK2 NTRK3 SORT1
Entrez ID		4908
HPRD ID		01219
Ensembl ID		ENSG00000185652
Uniprot IDs		P20783
PDB IDs		1B8K 1BND 1NT3 3BUK
Enriched GO Terms of Interacting Partners?
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