MVK

Description		mevalonate kinase
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GO Annotations	Cellular Component	Peroxisome Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding Mevalonate Kinase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Isoprenoid Biosynthetic Process Phosphorylation Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Negative Regulation Of Inflammatory Response
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs		Farnesyl thiopyrophosphate
Diseases
GWAS		Aspartate aminotransferase levels ( 29403010) Cataracts ( 34127677) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 24097068 18193043 20864672 19060906 30275531 25961943 20686565) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 29403010) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 32888494) Neutrophil count ( 29403010) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red cell distribution width ( 28957414) Serum metabolite levels ( 33031748)
Interacting Genes		9 interacting genes: EIF4E2 EWSR1 GLTP HIP1R POT1 PTPN11 RNF141 SELPLG TERF1
Entrez ID		4598
HPRD ID		02015
Ensembl ID		ENSG00000110921
Uniprot IDs		B2RDU6 B7Z301 F5H8H2 Q03426
PDB IDs		2R3V
Enriched GO Terms of Interacting Partners?
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