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MT3
Description
metallothionein 3
Image
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Mitochondrial Outer Membrane
Rough Endoplasmic Reticulum
Cytosol
Ribosome
Microtubule
Plasma Membrane
Synaptic Vesicle
Postsynaptic Density
Inclusion Body
Axon
Dendritic Spine
Perinuclear Region Of Cytoplasm
Astrocyte End-foot
Molecular Function
Copper Ion Binding
Protein Binding
Zinc Ion Binding
Antioxidant Activity
Protein Kinase Activator Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Cadmium Ion Binding
Metal Ion Binding
Biological Process
Response To Hypoxia
Positive Regulation Of Protein Phosphorylation
Energy Reserve Metabolic Process
Cholesterol Catabolic Process
Zinc Ion Transport
Cellular Metal Ion Homeostasis
Cellular Zinc Ion Homeostasis
Apoptotic Process
Brain Development
Detoxification Of Copper Ion
Negative Regulation Of Autophagy
Positive Regulation Of Gene Expression
Positive Regulation Of Necrotic Cell Death
Positive Regulation Of Cell Death
Negative Regulation Of Neuron Projection Development
Astrocyte Development
Histone Modification
Removal Of Superoxide Radicals
Negative Regulation Of Cell Growth
Negative Regulation Of Axon Extension
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Response To Food
Activation Of Protein Kinase B Activity
Leptin-mediated Signaling Pathway
Cellular Response To Oxidative Stress
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Negative Regulation Of Apoptotic Process
Positive Regulation Of Catalytic Activity
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Kinase B Signaling
Negative Regulation Of Neuron Apoptotic Process
Cellular Lipid Catabolic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Protein Stabilization
Negative Regulation Of Oxidoreductase Activity
Zinc Ion Homeostasis
Cadmium Ion Homeostasis
Regulation Of Protein Glycosylation
Negative Regulation Of Necrotic Cell Death
ERK1 And ERK2 Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Cadmium Ion
Cellular Response To Copper Ion
Cellular Response To Zinc Ion
Cellular Response To Hypoxia
Cellular Response To Nitric Oxide
Positive Regulation Of Lysosomal Membrane Permeability
Negative Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Hydrogen Peroxide Catabolic Process
Positive Regulation Of Oxygen Metabolic Process
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Metallothioneins bind metals
Metallothioneins bind metals
Drugs
Zinc
Silver
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Interacting Genes
2 interacting genes:
TERF2IP
TTR
Entrez ID
4504
HPRD ID
00752
Ensembl ID
ENSG00000087250
Uniprot IDs
A0A024R6R7
P25713
PDB IDs
2F5H
2FJ4
2FJ5
Enriched GO Terms of Interacting Partners
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