FADS3

Description		fatty acid desaturase 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding Oxidoreductase Activity, Acting On Paired Donors, With Oxidation Of A Pair Of Donors Resulting In The Reduction Of Molecular Oxygen To Two Molecules Of Water
	Biological Process	Lipid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Sphingolipid Metabolic Process
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma (adult onset) ( 31036433) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Cholesterol, total ( 24097068 19060911 25961943 20686565) Fatty acid desaturase activity (serum) ( 30453627) Glycated hemoglobin levels ( 34059833) Glycerophospholipid levels ( 26068415) HDL cholesterol ( 24097068 19060906 19060911 25961943 20686565) HDL cholesterol levels ( 28334899) Laryngeal squamous cell carcinoma ( 25194280) LDL cholesterol ( 24097068 19060911 25961943 20686565) LDL cholesterol levels ( 28334899) Lipid metabolism phenotypes ( 22286219) Metabolite levels ( 23823483 23378610 22916037) Oleic acid (18:1n-9) levels ( 23362303) Phospholipid levels (plasma) ( 22359512) Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377) Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Red blood cell fatty acid levels ( 25500335) Response to statin therapy ( 20339536) Rheumatoid arthritis ( 30423114 24390342) Serum metabolite levels (CMS) ( 31636271) Sphingolipid d18:1/d18:2 ratio ( 31862735) Sphingolipid levels ( 19798445 26068415 22359512) Stearic acid (18:0) levels ( 23362303) Total cholesterol levels ( 28334899) Triglyceride levels ( 28334899) Triglycerides ( 24097068 19060906 25961943 20686565) Urate levels ( 31578528)
Interacting Genes		2 interacting genes: DHRSX MDN1
Entrez ID		3995
HPRD ID		07547
Ensembl ID		ENSG00000221968
Uniprot IDs		A0A024R564 Q9Y5Q0
PDB IDs
Enriched GO Terms of Interacting Partners?
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