LAMB2

Description		laminin subunit beta 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Laminin-3 Complex Endoplasmic Reticulum Lumen Neuromuscular Junction Synaptic Cleft Laminin Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Axon Guidance Neuromuscular Junction Development Visual Perception Animal Organ Morphogenesis Tissue Development Astrocyte Development Schwann Cell Development Cell Migration Substrate Adhesion-dependent Cell Spreading Axon Extension Involved In Regeneration Retina Development In Camera-type Eye Basement Membrane Assembly Metanephric Glomerular Visceral Epithelial Cell Development Metanephric Glomerular Basement Membrane Development
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mood instability ( 31168069) Myocardial infarction ( 33532862) PR interval ( 32439900) Resting heart rate ( 27798624) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: ATXN7 CIP2A CTNNB1 HOXA1 KPNA2 ORC5 PIK3R2 PLEKHA5 RBL1 STAT3 TSR2 ZNF512B
Entrez ID		3913
HPRD ID		01034
Ensembl ID		ENSG00000172037
Uniprot IDs		P55268
PDB IDs
Enriched GO Terms of Interacting Partners?
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