ITPK1

Description		inositol-tetrakisphosphate 1-kinase
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GO Annotations	Cellular Component	Cytoplasm Cytosol Apical Plasma Membrane
	Molecular Function	Magnesium Ion Binding Inositol Tetrakisphosphate 6-kinase Activity Catalytic Activity ATP Binding Hydrolase Activity Isomerase Activity Inositol Tetrakisphosphate 1-kinase Activity Inositol-1,3,4-trisphosphate 6-kinase Activity Inositol-1,3,4-trisphosphate 5-kinase Activity
	Biological Process	Signal Transduction Blood Coagulation Neural Tube Development Inositol Trisphosphate Metabolic Process Inositol Phosphorylation Necroptotic Process
Pathways		Synthesis of pyrophosphates in the cytosol Synthesis of IP3 and IP4 in the cytosol Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Body mass index ( 26426971) Chronic obstructive pulmonary disease ( 30804561) Endometriosis ( 23472165) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 31562340) Migraine ( 27182965 27322543) Monocyte count ( 32888494) Platelet count ( 22139419 32888494) Plateletcrit ( 32888494 27863252) Spleen volume ( 34128465) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: COPS8 GPS1 JUN NFKBIA TP53 TRAF2
Entrez ID		3705
HPRD ID		03501
Ensembl ID		ENSG00000100605
Uniprot IDs		A0A024R6H3 Q13572
PDB IDs		2ODT 2Q7D 2QB5
Enriched GO Terms of Interacting Partners?
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