INPPL1

Description		inositol polyphosphate phosphatase like 1
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GO Annotations	Cellular Component	Nucleus Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Nuclear Speck Lamellipodium Filopodium
	Molecular Function	Actin Binding Protein Binding SH3 Domain Binding Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity SH2 Domain Binding
	Biological Process	Endochondral Ossification Immune System Process Glucose Metabolic Process Phosphatidylinositol Biosynthetic Process Endocytosis Actin Filament Organization Cell Adhesion Negative Regulation Of Cell Population Proliferation Post-embryonic Development Negative Regulation Of Gene Expression Response To Insulin Phosphatidylinositol Dephosphorylation Ruffle Assembly
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of IP3 and IP4 in the cytosol Interleukin receptor SHC signaling
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Diseases
GWAS		Heart rate response to recovery post exercise (10 sec) ( 29497042)
Interacting Genes		24 interacting genes: ABL1 AR ARAP3 BCAR1 CBL CD4 CSF1R DRD2 EGFR ERBB2 ERBB3 ERBB4 FCGR2B FLNC GAB1 HID1 HYOU1 KMT2A MET SHC1 SORBS1 SORBS3 SRC UBC
Entrez ID		3636
HPRD ID		02900
Ensembl ID		ENSG00000165458
Uniprot IDs		O15357
PDB IDs		2K4P 2KSO 2MK2 3NR8 4A9C 5OKM 5OKN 5OKO 5OKP 6SQU 6SRR
Enriched GO Terms of Interacting Partners?
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