IL5

Description		interleukin 5
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Interleukin-5 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Positive Regulation Of Immunoglobulin Production Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Positive Regulation Of B Cell Proliferation Positive Regulation Of Eosinophil Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Podosome Assembly
Pathways		Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs		Pranlukast Reslizumab Mepolizumab
Diseases
GWAS		Asthma ( 31959851 31619474) Eosinophil counts ( 29403010 19198610 32888494) Inflammatory bowel disease ( 23128233) Pediatric autoimmune diseases ( 26301688) Rosacea symptom severity ( 29771307)
Interacting Genes		2 interacting genes: HSPA9 IL5RA
Entrez ID		3567
HPRD ID		00997
Ensembl ID		ENSG00000113525
Uniprot IDs		P05113
PDB IDs		1HUL 3QT2 3VA2
Enriched GO Terms of Interacting Partners?
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