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DNAJB2

Description DnaJ heat shock protein family (Hsp40) member B2
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GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • Intrinsic Component Of Endoplasmic Reticulum Membrane
  • Nuclear Membrane
Molecular Function
  • ATPase Activator Activity
  • Protein Binding
  • Hsp70 Protein Binding
  • Ubiquitin Binding
  • Unfolded Protein Binding
  • Chaperone Binding
  • Ubiquitin-dependent Protein Binding
Biological Process
  • Response To Unfolded Protein
  • Negative Regulation Of Cell Population Proliferation
  • Negative Regulation Of Cell Growth
  • Ubiquitin-dependent ERAD Pathway
  • Regulation Of Protein Ubiquitination
  • Negative Regulation Of Protein Binding
  • Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Positive Regulation Of ATPase Activity
  • Protein Refolding
  • Regulation Of Catalytic Activity
  • Chaperone-mediated Protein Folding
  • Neuron Cellular Homeostasis
  • Negative Regulation Of Inclusion Body Assembly
  • Regulation Of Chaperone-mediated Protein Folding
Pathways
Drugs
Diseases
GWAS
Interacting Genes 9 interacting genes: CSNK2A1 FBXO25 HSPA4 MAP3K1 RPS27A SMAD4 UBA52 UBC UBQLN1
Entrez ID 3300
HPRD ID 07249
Ensembl ID ENSG00000135924
Uniprot IDs P25686
PDB IDs 2LGW
Enriched GO Terms of Interacting Partners?
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