HSD17B1

Description		hydroxysteroid 17-beta dehydrogenase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Estradiol 17-beta-dehydrogenase Activity Steroid Binding Protein Binding Testosterone Dehydrogenase [NAD(P)] Activity Dihydrotestosterone 17-beta-dehydrogenase Activity Protein Homodimerization Activity 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Testosterone Dehydrogenase (NAD+) Activity Testosterone 17-beta-dehydrogenase (NADP+) Activity NADP Binding NADP+ Binding 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity Estradiol Binding
	Biological Process	Steroid Biosynthetic Process Estrogen Biosynthetic Process Estrogen Metabolic Process Bone Development Testosterone Biosynthetic Process Cellular Response To Metal Ion
Pathways		Estrogen biosynthesis The canonical retinoid cycle in rods (twilight vision)
Drugs		NADH Androstenedione Androstanedione Equilin EM-1745 Stanolone Nicotinamide adenine dinucleotide phosphate Stanolone acetate
Diseases
GWAS		Eczema ( 31361310) Parkinson's disease ( 27182965) Pulse pressure ( 28135244 30578418)
Interacting Genes		2 interacting genes: ALOX5 PTEN
Entrez ID		3292
HPRD ID		00185
Ensembl ID		ENSG00000108786
Uniprot IDs		A0A0A0MQS7 P14061
PDB IDs		1A27 1BHS 1DHT 1EQU 1FDS 1FDT 1FDU 1FDV 1FDW 1I5R 1IOL 1JTV 1QYV 1QYW 1QYX 3DEY 3DHE 3HB4 3HB5 3KLM 3KLP 3KM0 6CGC 6CGE 6DTP 6MNC 6MNE
Enriched GO Terms of Interacting Partners?
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