GSPT1

Description		G1 to S phase transition 1
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GO Annotations	Cellular Component	Cytosol Translation Release Factor Complex
	Molecular Function	RNA Binding Translation Release Factor Activity GTPase Activity Protein Binding GTP Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translational Termination Translation Regulation Of Translational Termination Protein Methylation
Pathways		Eukaryotic Translation Termination Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494) Menopause (age at onset) ( 26414677) Red blood cell count ( 32888494) Testicular germ cell tumor ( 26503584)
Interacting Genes		12 interacting genes: ATXN1 BIRC2 BIRC3 CDKN2A CRBN DDB1 ETF1 GSPT2 HINFP PABPC1 PIK3R1 XIAP
Entrez ID		2935
HPRD ID		00753
Ensembl ID		ENSG00000103342
Uniprot IDs		B2RCT6 P15170 Q7KZX8
PDB IDs		3E1Y 3J5Y 3KUI 4D61 5HXB 5LZT 6XK9
Enriched GO Terms of Interacting Partners?
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