ARHGAP35

Description		Rho GTPase activating protein 35
Image
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Actin Cytoskeleton Ciliary Basal Body
	Molecular Function	DNA Binding GTPase Activity GTPase Activator Activity GTP Binding Phospholipid Binding
	Biological Process	Neural Tube Closure Signal Transduction Axon Guidance Axonal Fasciculation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Cell Migration Central Nervous System Neuron Axonogenesis Mammary Gland Development Forebrain Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cellular Response To Extracellular Stimulus Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Rho Protein Signal Transduction Camera-type Eye Development Negative Regulation Of Vascular Permeability Wound Healing, Spreading Of Cells Positive Regulation Of Cilium Assembly Regulation Of Axonogenesis Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Neuron Projection Guidance
Pathways		Sema4D mediated inhibition of cell attachment and migration PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33339817) Brain morphology (MOSTest) ( 32665545) Deep white matter hyperintensities ( 32517579)
Interacting Genes		6 interacting genes: CDC42 GRB2 KRT31 PTPRZ1 RAC1 SRC
Entrez ID		2909
HPRD ID		05592
Ensembl ID		ENSG00000160007
Uniprot IDs		Q9NRY4
PDB IDs		2K85 3C5H 3FK2 6PXC 6WAY
Enriched GO Terms of Interacting Partners?
Tagcloud ?