ANGPT2

Description		angiopoietin 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Plasma Membrane Cell Projection Collagen-containing Extracellular Matrix
	Molecular Function	Signaling Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding Metal Ion Binding
	Biological Process	Angiogenesis Response To Hypoxia Signal Transduction Germ Cell Development Response To Radiation Response To Mechanical Stimulus Response To Glucose Gene Expression Negative Regulation Of Cell-substrate Adhesion Response To Organic Cyclic Compound Response To Activity Negative Regulation Of Angiogenesis Animal Organ Regeneration Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Tie Signaling Pathway Negative Regulation Of Positive Chemotaxis Maternal Process Involved In Female Pregnancy Cellular Response To Growth Factor Stimulus Glomerulus Vasculature Development
Pathways		Tie2 Signaling
Drugs		Faricimab
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576) Dental caries (decayed and filled deciduous teeth) ( 31533690) Intraocular pressure ( 29617998 29785010 30054594) Metabolite levels ( 23823483) Response to cytidine analogues (gemcitabine) ( 24483146)
Interacting Genes		6 interacting genes: ANGPT1 ANXA7 CDKN1A CSNK2B ITGA5 TEK
Entrez ID		285
HPRD ID		03563
Ensembl ID		ENSG00000091879
Uniprot IDs		O15123
PDB IDs		1Z3S 1Z3U 2GY7 4JZC 4ZFG
Enriched GO Terms of Interacting Partners?
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