GPC1

Description		glypican 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Endosome Golgi Lumen Cytosol Plasma Membrane Cell Surface Extracellular Matrix Intrinsic Component Of Plasma Membrane Lysosomal Lumen Membrane Raft Synapse Anchored Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Copper Ion Binding Fibroblast Growth Factor Binding Laminin Binding
	Biological Process	Schwann Cell Differentiation Cell Migration Heparan Sulfate Proteoglycan Catabolic Process Myelin Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization To Membrane Positive Regulation Of Skeletal Muscle Cell Differentiation
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Signaling by ROBO receptors Defective B3GALT6 causes EDSP2 and SEMDJL1 Retinoid metabolism and transport
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) BMI x SSRI levels interaction in schizophrenia or bipolar disorder ( 33824429) Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125)
Interacting Genes		5 interacting genes: APP COL18A1 SLIT1 SLIT2 VEGFA
Entrez ID		2817
HPRD ID		02671
Ensembl ID		ENSG00000063660
Uniprot IDs		A0A384NPH9 H7C410 P35052
PDB IDs		4ACR 4AD7 4BWE 4YWT
Enriched GO Terms of Interacting Partners?
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