GLDC

Description		glycine decarboxylase
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Glycine Cleavage Complex
	Molecular Function	Glycine Dehydrogenase (decarboxylating) Activity Electron Transfer Activity Glycine Binding Lyase Activity Enzyme Binding Pyridoxal Phosphate Binding Protein Homodimerization Activity Pyridoxal Binding
	Biological Process	Glycine Catabolic Process Glycine Decarboxylation Via Glycine Cleavage System Electron Transport Chain Response To Methylamine Protein-containing Complex Assembly Response To Lipoic Acid
Pathways		Glycine degradation
Drugs		Pyridoxal phosphate
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Glycine levels ( 31070104 30837465) Height ( 31562340) Metabolite levels ( 23823483) Metabolite levels (small molecules and protein measures) ( 27005778) Overall survival in osteosarcoma ( 29210060) Periodontal microbiota ( 22699663) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		3 interacting genes: DNAI1 IFNA1 TLR10
Entrez ID		2731
HPRD ID		01996
Ensembl ID		ENSG00000178445
Uniprot IDs		P23378
PDB IDs		6I33 6I34 6I35
Enriched GO Terms of Interacting Partners?
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