GFRA2

Description		GDNF family receptor alpha 2
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GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Receptor Complex
	Molecular Function	Glial Cell-derived Neurotrophic Factor Receptor Activity Signaling Receptor Activity
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Negative Regulation Of Protein Autophosphorylation Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway
Pathways		NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Diisocyanate-induced asthma ( 25918132) Frontotemporal dementia ( 29724592) Frontotemporal dementia with GRN mutation ( 29724592) Migraine with aura ( 23793025) Neuropathic pain in type 2 diabetes ( 24974787) Nicotine dependence symptom count ( 25555482) Pelvic organ prolapse (moderate/severe) ( 26545240) Trunk fat mass ( 28552196) Verbal declarative memory ( 25648963)
Interacting Genes		3 interacting genes: GDNF NRTN PPP3CC
Entrez ID		2675
HPRD ID		11801
Ensembl ID		ENSG00000168546
Uniprot IDs		O00451
PDB IDs		5MR4 5MR5 6GL7 6Q2O 6Q2R
Enriched GO Terms of Interacting Partners?
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