GBP1

Description		guanylate binding protein 1
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Vesicle Membrane Actin Cytoskeleton Cytoplasmic Vesicle
	Molecular Function	Actin Binding GTPase Activity Protein Binding GTP Binding GDP Binding Enzyme Binding Cytokine Binding Spectrin Binding Identical Protein Binding Protein Homodimerization Activity Hsp90 Protein Binding
	Biological Process	Negative Regulation Of Interleukin-2 Production Regulation Of Calcium-mediated Signaling Negative Regulation Of T Cell Receptor Signaling Pathway Defense Response To Virus Negative Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Protein Localization To Vacuole Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Protein Localization To Plasma Membrane
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Remission after SSRI treatment in MDD or openness ( 29559929) Serum metabolite levels ( 33031748)
Interacting Genes		3 interacting genes: FNTA FNTB PTBP2
Entrez ID		2633
HPRD ID		02681
Ensembl ID		ENSG00000117228
Uniprot IDs		P32455
PDB IDs		1DG3 1F5N 2B8W 2B92 2BC9 2D4H 6K1Z 6K2D 6LOJ
Enriched GO Terms of Interacting Partners?
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