FBXW8

Description		F-box and WD repeat domain containing 8
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol SCF Ubiquitin Ligase Complex Cul7-RING Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Golgi Organization Cell Population Proliferation Protein Ubiquitination Positive Regulation Of Dendrite Morphogenesis Labyrinthine Layer Blood Vessel Development Positive Regulation Of Transcription Factor Catabolic Process
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Brain structure ( 22504417) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) HATA volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Marginal zone lymphoma or rheumatoid arthritis ( 31407831) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459)
Interacting Genes		7 interacting genes: CUL7 IRS1 MYC PBRM1 RBX1 SKP1 UBE2D3
Entrez ID		26259
HPRD ID		16427
Ensembl ID		ENSG00000174989
Uniprot IDs		Q8N3Y1
PDB IDs
Enriched GO Terms of Interacting Partners?
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