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STAP1
Description
signal transducing adaptor family member 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Phosphotyrosine Residue Binding
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
Macrophage Colony-stimulating Factor Receptor Binding
Protein Binding
Phospholipid Binding
Protein Kinase Binding
Signaling Adaptor Activity
Biological Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Gene Expression
Negative Regulation Of Macrophage Chemotaxis
Negative Regulation Of Phosphorylation
Positive Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Phagocytosis, Engulfment
Cellular Response To Lipopolysaccharide
Negative Regulation Of Ruffle Assembly
Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway
Positive Regulation Of Microglial Cell Activation
Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity
Negative Regulation Of Microglial Cell Migration
Positive Regulation Of Microglial Cell Mediated Cytotoxicity
Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Drugs
Diseases
GWAS
Regular attendance at a pub or social club (
29970889
)
Interacting Genes
15 interacting genes:
AR
EGFR
ERBB2
ERBB3
ERBB4
GAB1
GATA3
GRIPAP1
KIT
MET
PTK2B
RETREG3
SH3KBP1
TEC
URI1
Entrez ID
26228
HPRD ID
16053
Ensembl ID
ENSG00000035720
Uniprot IDs
A0A024RD91
Q9ULZ2
PDB IDs
1X1F
3MAZ
Enriched GO Terms of Interacting Partners
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