GART

Description		phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome
	Molecular Function	Phosphoribosylamine-glycine Ligase Activity Phosphoribosylformylglycinamidine Cyclo-ligase Activity Phosphoribosylglycinamide Formyltransferase Activity ATP Binding Metal Ion Binding
	Biological Process	Brainstem Development Purine Nucleotide Biosynthetic Process 'de Novo' IMP Biosynthetic Process Glycine Metabolic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Response To Organic Substance Response To Inorganic Substance Cerebellum Development Cerebral Cortex Development Adenine Biosynthetic Process Tetrahydrofolate Biosynthetic Process
Pathways		Purine ribonucleoside monophosphate biosynthesis
Drugs		Pemetrexed Glycinamide Ribonucleotide N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid
Diseases
GWAS		Crohn's disease ( 23128233) Educational attainment ( 25201988) Psoriasis ( 25854761)
Interacting Genes		10 interacting genes: CDC42 IFNAR1 JUN KPNA2 NMI OGT PXN TIAM1 TMPRSS15 TRAF6
Entrez ID		2618
HPRD ID		00716
Ensembl ID		ENSG00000159131
Uniprot IDs		P22102 Q59HH3
PDB IDs		1MEJ 1MEN 1MEO 1NJS 1RBM 1RBQ 1RBY 1RBZ 1RC0 1RC1 1ZLX 1ZLY 2QK4 2V9Y 4EW1 4EW2 4EW3 4ZYT 4ZYU 4ZYV 4ZYW 4ZYX 4ZYY 4ZYZ 4ZZ0 4ZZ1 4ZZ2 4ZZ3 5J9F
Enriched GO Terms of Interacting Partners?
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