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BAMBI

Description BMP and activin membrane bound inhibitor
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • Frizzled Binding
  • Type II Transforming Growth Factor Beta Receptor Binding
  • Protein Binding
Biological Process
  • Transforming Growth Factor Beta Receptor Signaling Pathway
  • Positive Regulation Of Cell Population Proliferation
  • Regulation Of Cell Shape
  • Positive Regulation Of Epithelial To Mesenchymal Transition
  • Cell Migration
  • Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
  • Negative Regulation Of BMP Signaling Pathway
  • Positive Regulation Of Protein Binding
  • Negative Regulation Of Osteoblast Differentiation
  • Positive Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
  • Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS
  • Cataracts ( 34127677)
  • Cataracts (operation) ( 31816047)
  • Fasting glucose change (long-term) ( 31263163)
  • Intraocular pressure ( 29617998)
  • Metabolite levels ( 23823483)
  • Percentage gas trapping ( 26030696)
  • Preeclampsia ( 23551011)
Interacting Genes 9 interacting genes: ACVR1 ACVR1B ACVRL1 BMPR1A BMPR1B NKG7 SELENOF SOX30 TGFBR1
Entrez ID 25805
HPRD ID 05117
Ensembl ID ENSG00000095739
Uniprot IDs Q13145
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025